Alyssa Milano as Samantha Micelli (Who’s The Boss),Jennifer Mancini (Melrose Place) and Phoebe Halliwell (Charmed).
Jennifer Love Hewitt as Sarah Reeves (Party of 5),Melinda Gordon (Ghost Whisperer) and Maddie Han (911).
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* David Boreanaz, played Angel on Buffy and on Angel from 1997-2004. Then played Booth on Bones from 2005 to 2017. Then played Jason Hayes on SEAL Team, which I’ve never heard anyone say they watch but it ran from 2017 to 2024, so people must have liked it.
* Emily VanCamp started on Everwood, then had Brothers and Sisters; Revenge; and The Resident.
Steve Carell (The Morning Show, The Office, The Patient
Julia Louis Dreyfus as Elaine in Seinfeld, Christine in New Adventures of Old Christine, and then Selina Meyer in Veep.
Nathan Fillion (Firefly, Castle, The Rookie)
https://i.redd.it/gdpnp74b8huf1.gif
Tichina Arnold. Pam – Martin, Rochelle -Everybody Hates Chris, Tina – The Neighborhood.
Terry O’Quinn has been on TV for decades.
Frank Oz (this is cheating)
Kaley Cuoco was on a roll with 8 Simple Rules (2002-2005), The Big Bang Theory (2007-2019), and The Flight Attendant (2020-2022). I know she was also on Charmed between 8SR and TBBT, but I didn’t watch that and I think she was a less-popular replacement for one of the mains.
Allison Janney is so close.. CG Cregg, Bonnie Plunkett. Please god someone give her another show!
Walton Goggins on The Shield, and then Justified, and then… take your pick
Peter Krause (Sports Night, Six Feet Under, Parenthood, 9-1-1).
LeVar Burton: Reading Rainbow, Roots, Star Trek: The Next Generation
Kate Mulgrew: Ryan’s Hope, Star Trek: Voyager, Orange is the New Black
Ron Howard: Andy Griffith, Happy Days, Arrested Development
Bob Odenkirk’s gotta top that list imo. From Breaking Bad to Better Call Saul and then to Fargo, dude’s been killing it on the small screen.
Heather Locklear on Dynasty, Spin City, TJ Hooker, Melrose Place…
Betty White as Sue Ann Nivens in The Mary Tyler Moore Show, Rose Nylund in The Golden Girls, and Elka Ostrovsky in Hot in Cleveland.
Jason Segel – freaks and geeks, how I met your mother, shrinking.
Maybe freaks and geeks wasn’t a hit, but it was fucking great.
Kristen bell- Veronica mars, gossip girl, the good place
Ted Danson- Cheers, CSI, and The Good Place
Matt Smith- Doctor Who, the Crown, and House of the Dragon
Jean Smart: Designing Women, Frasier, Samantha Who, Hacks and MANY more!
Hugh Laurie- a Bit of Fry and Laurie, Blackadder, and House
Katey Sagal- Married with Children, Sons of Anarchy, and Futurama
Kristen Bell, Veronica Mars, A Good Place, Nobody Wants This
John Ritter: Walton, Threes Company, 8 Simple Rules.
Michael C Hall: Dexter, Six Feet Under, Safe
Bryan Cranston: Malcolm in the Middle, Breaking Bad, Your Honor
Connie Britton – Friday Night Lights, Nashville, American Horror Story, White Lotus, 9-1-1 and more.
Elisabeth Moss – the West Wing, Mad Men and Handmaids Tale
Milo Ventimiglia – Gilmore Girls, Heroes, This Is Us
Adam Brody – The OC, Gilmore Girls, Nobody Wants This